The Function Of The Hair Follicle Stem Cells - 1239 Words

An adult stem cell’s niche is responsible for the preservation of the stem cell’s undifferentiated state through either intrinsic or extrinsic expression of specific proteins. Hair follicle stem cells are responsible for not only its self-renewal but also in the production of rapidly multiplying cells. The stem cells of the hair follicle are for temporary increase in cells, and are created by the differentiation of hair follicle stem cells. The focus of this essay will be to analyze a specific protein within the hair follicle stem cell BMP, bone morphogenetic proteins. Through intrinsic expression, Bone morphogenetic proteins (BMPs) are able to function in multi levels and are in charge for the transforming growth factor beta (TGFbeta). These proteins are crucial for the maintenance and the proliferation of hair follicle stem cells. Bone morphogentic proteins have the ability to affect other molecules that are part of the niche, which boosts or limits particular cell ular functions to the needs of the human body and niche. This paper will discuss two experiments conducted that exhibit the function of BMP. One experiment will examine the results of BMP deletion in genetically modified dermal papilla cells patched onto mice that had no hair. The second scientific experiment will demonstrate the effects of excess and limited quantities of BMP expression in vitro on isolated chick otic vesicles. From these experiments scientists can foresee the future in developing variousShow MoreRelatedLab Report1388 Words   |  6 PagesAbstract: Tissue regeneration through cell differentiation from one cell type to another is a phenomenon occurs in some species of fish and amphibians, however, mammals are incapable of reprogramming one cell lineage to achieve a similar result. Specifically, in human and mouse wound healing procedure normally generate scar with high collagen deposition, regenerated skin which lacks some features such as hair follicle and cutaneous fat. A recent study shows that a large skin wound in a mouse modelRead MoreThe Skin Or Integument System1165 Words   |  5 Pagesintegument system is composed of many different sections and accessories, functions for multiple outlets, and falls at risk of disease everyday. The integument is divided by two main sections, the epidermis and dermis. (Amirlak) The outermost layer of the skin is the epidermis. The epidermis is composed mostly of stratified squamous epithelium, more specifically keratinocytes, which then become multiple layers of dead keratinized cells. (Saladin) The superficial layer of the epidermis is called the stratumRead MoreThe Body And The Outer Environment1218 Words   |  5 Pagesthe key elements of the skin’s structure and functions to provide an in-depth understanding on the skins biology and how to apply this knowledge to the beauty industry. Knowledge of skin structure and promotion of skin health Function and role of the skin 1.1 Explain the Integumentary system The integumentary system covers the whole body and is made up of several layers.The integumentary system consists of the skin and its derivatives including hair, glands, nails and specialised receptors ï  ¶Read MoreReview Questions Integumentary System1217 Words   |  5 Pagesmade up of Stratified Squamous Epithelium. 3. Name and discuss the four cell types found in the epidermis. (Give the structure and function of each) * Keratinocytes- 90% filled with keratin and have a waterproof barrier. * Melanocytes- 8% produce melanin pigment and pass them to the keratinocytes. * Langerhans cells- phagocytes from the immune system and are easily damaged by UV light * Merkle cells- located in deepest layer of hairless skin and they are the sensory transductionRead MoreCan Skin Dermal Papilla (DP) Cells Differentiate into Induced Pluripotent Stem Cells?578 Words   |  3 Pagespapilla (DP) cells can differentiate into induced pluripotent stem cells (iPSCs) by using the transcription factor, OCT4, instead of using all four transcription factor, OCT4, Sox2, Klf4, and c-Myc, which are usually used to differentiate somatic cells into stem cells. The scientists came up with the question because two out of the four transcription factors, Klf4 and c-Myc, are oncogenic gene, thereby it is best to replace these genes with other safer alternatives. Reprogramming cells into inducedRead MoreThe Human Body And All The Organ System1462 Words   |  6 Pagesa constant state of movement even when seemingly still. This constant movement is crucial for the human body and all the organ systems it contains. Movement although overlooked is more complicate than many would believe. The human body has many functions which are maintained by the movement of muscles and blood, as well as other bi-products of the organ systems. The Integumentary, Cardiovascular, and Tissue systems are capable of movement both internal and external allowing for the continuous cycleRead MoreStudy Guide Ch 5 Integumentary System K1521 Words   |  7 Pagesvolunteered to help at a hospital for children with cancer. When she first entered the cancer ward, she was upset by the fact that most of the children had no hair. What is the explanation for their baldness? Chemotherapy drugs used to treat cancer kill the most rapidly dividing cells in the body, including many matrix cells in the hair follicles; thus the hair falls out. 2. A new mother brings her infant to the clinic, worried about a yellowish, scummy deposit that has built up on the baby’s scalp. What isRead MorePhases of Wound Healing2433 Words   |  10 PagesDisturbances, abnormalities and delays in any of the above stages may lead to impaired healing or even chronic wounds. In adults, this process of normal healing takes place in the following steps (1)rapid haemostasis (2)appropriate inflammation (3)mesenchymal cell differentiation, proliferation, and migration to the wound site (4)suitable angiogenesis (5)prompt re-epithelialization and (6) proper synthesis, cross-linking, and alignment of collagen to provide strength to the healing tissue. Immediately afterRead MoreThe Importance Of Homeostasis And A State Of Equilibrium Reached Through Physiological Processes1169 Words   |  5 Pagesliving things use cells, tissues, organs, and organ systems to counteract physical changes. Using a variety of different tissues, organs are formed to accomplish specific tasks. The four main types of tissues are epithelial tissue, connective tissue, muscular tissue, and nervous tissue. Several sublevels exist for each type of tissue. Epithelial tissue covers body surfaces and lines body cavities. The three main kinds of Epithelial tissue are squamous which is composed of flat cells, cuboidal, whichRead MoreA Research Study On Stem Cell Research Essay907 Words   |  4 PagesStem Cell Research A stem cell is defined as having â€Å"the ability to make specialized cells for various tissues in the body, such as heart muscle, brain tissue, and liver tissue† (umm.edu) Two of the most commonly studied stem cells are adult and embryonic. Adult stem cells are cells that have already became specialized, such as heart or muscle tissue. Embryonic cells on the other hand are still in development. This means that with some modifying, then an embryonic stem cell can develop into almost